Anaphylatoxine sind Abbauprodukte des menschlichen Körpers. Es sind Proteine, aktivierte Teilkomplexe des Komplementsystems, die bei akuten allergischen Reaktionen durch Auslösung des Mastzellen-Zerfalls Histamin freisetzen.


Anaphylatoxine bewirken

  • Spasmen glatter Muskelfasern, z. B. Bronchialspasmen
  • Steigerung der Durchlässigkeit der Blutkapillaren durch Histaminfreisetzung aus Mastzellen (Histamineffekt)
  • zunehmende Chemotaxis, also biochemisch ausgelöste Bewegungsreaktionen z. B. weißer Blutkörperchen

In anderen Sprachen

  • englischer Ausdruck: anaphylatoxin
  • französischer Ausdruck: anaphylatoxine

Siehe auch: Atopie (Medizin)

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  • Anaphylatoxin — Anaphylatoxins, or anaphylotoxins, are fragments (C3a, C4a and C5a) that are produced during the pathways of the complement system.cite journal | author = Hugli TE | title = Biochemistry and biology of anaphylatoxins | journal = Complement |… …   Wikipedia

  • anaphylatoxin — Low molecular weight substances generated by the activation of complement; the biologically active complement components are derived from C3, C4, and C5 and lead to increased vascular permeability as a result of the degranulation of primarily… …   Medical dictionary

  • anaphylatoxin — Originally used of an antigen that reacted with an IgE antibody thus precipitating reactions of anaphylaxis. Now restricted to defining a property of complement fragments C3a and C5a, both of which bind to the surfaces of mast cells and basophils …   Dictionary of molecular biology

  • anaphylatoxin — noun Any of several toxic substances that trigger anaphylaxis …   Wiktionary

  • Anaphylatoxin — Ana|phyla|toxi̱n [Kurzw. aus ↑Anaphylaxie u. ↑Toxin] s; s, e: der hypothetische Giftstoff (Anaphylaktogen) des eine Anaphylaxie erzeugenden Fremdeiweißes …   Das Wörterbuch medizinischer Fachausdrücke

  • anaphylatoxin — an·a·phyl·a·tox·in …   English syllables

  • anaphylatoxin — ˌanəˌfiləˈtäksə̇n noun ( s) Etymology: International Scientific Vocabulary anaphyla (from New Latin anaphylaxis) + toxin : a hypothetical substance formerly regarded as responsible for the symptoms of anaphylaxis …   Useful english dictionary

  • Anaphylatoxin receptors — The anaphylatoxin receptors are a group of G protein coupled receptors which bind anaphylatoxins.cite journal | author = Fukuoka Y, Nielsen LP, Hugli TE | title = Characterization of receptors to the anaphylatoxins on isolated cells | journal =… …   Wikipedia

  • anaphylatoxin inactivator — An α globulin (MW 300,000) which destroys the activity of the anaphylatoxic complement fragments. See anaphylatoxin. * * * (AI) a serum carboxypeptidase that destroys the anaphylatoxin activity of C3a, C4a, and C5a by removing C terminal arginyl… …   Medical dictionary

  • C3a receptor — The C3a receptor also known as complement component 3a receptor 1 (C3AR1) is a G protein coupled receptor protein involved in the complement system.cite journal | author = Roglic A, Prossnitz ER, Cavanagh SL, Pan Z, Zou A, Ye RD | title = cDNA… …   Wikipedia

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