Ankyrin
Die Struktur eines Teils der membranbindenden Struktur von Ankyrin

Ankyrine sind Repeat-Proteine, die wie Antikörper zu den Bindungsproteinen gehören. Ankyrine sind Cytoskelett-Proteine, die über dynamische, nicht-kovalente Bindungen mit integralen Membranproteinen interagieren und deren Verteilung innerhalb der Zellmembran mitbestimmen.


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  • Ankyrin — protein Name = ANK1, erythrocytic caption = Ribbon diagram of a fragment of the membrane binding domain of ankyrin R. From PDB|1N11. width = 250 HGNCid = 492 Symbol = ANK1 AltSymbols = AnkyrinR, Band2.1 EntrezGene = 286 OMIM = 182900 RefSeq = NM… …   Wikipedia

  • ankyrin — An erythrocyte membranal protein that binds spectrin. A deficiency in a. may lead to a type of hereditary spherocytosis. SYN: anchorin, syndein. [G. ankyra, anchor, + in] * * * an·ky·rin (angґkə rin) a membrane protein of e …   Medical dictionary

  • ankyrin — Globular protein (200 kD) that links spectrin and an integral membrane protein (Band III) in the erythrocyte plasma membrane. Isoforms exist in other cell types …   Dictionary of molecular biology

  • ankyrin — noun Any of a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin actin based membrane skeleton …   Wiktionary

  • ankyrin — …   Useful english dictionary

  • Ankyrin repeat — The ankyrin repeat is a 33 residue motif in proteins consisting of two alpha helices separated by loops, first discovered in signaling proteins in yeast Cdc10 and Drosophila Notch. Ankyrin repeats mediate protein protein interactions and are… …   Wikipedia

  • Ankyrin deficiency — Known also as hereditary spherocytosis (HS), this is a genetic disorder of the red blood cell membrane clinically characterized by anemia, jaundice (yellowing) and splenomegaly (enlargement of the spleen), due to deficiency of ankyrin, a protein… …   Medical dictionary

  • ankyrin repeat — See ANK repeat …   Dictionary of molecular biology

  • Deficiency, ankyrin — Known also as hereditary spherocytosis (HS), this is a genetic disorder of the red blood cell membrane clinically characterized by anemia, jaundice (yellowing) and splenomegaly (enlargement of the spleen), due to deficiency of ankyrin, a protein… …   Medical dictionary

  • ANK — ankyrin …   Medical dictionary

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